Our Ash Manna,
the only patented one.
2000 years of History
197 years of Industrial, scientific and cultural tradition
Today the Innovation of a raw material of absolute topicality, essential for creating finished products with unique therapeutic indications.
Mannaceutica is the only company in the world to produce innovative and exclusive therapeutic products based on Ash Manna, using a patented method developed by the Biochemistry Laboratory of the Department of Biological, Chemical and Pharmaceutical Sciences and Technologies STEBICEF of the University of Palermo.




Mannaceutics and Nutraceutics
The Ash Manna
Manna is a processed sap of some peculiar species of Ash tree, the Fraxinux Ornus L and the Fraxinus Angustifolia Vahl. It is a pharmacologically active natural product, with several therapeutic properties known today. Currently, thanks to the constant scientific research activity carried out by various university departments at national and international level, further possible important applications in the clinical field are being investigated, which project the Ash Manna from a thousand-year-old and traditional past, towards an innovative and specialized future in the field of modern medicine.

A family tradition: between innovation and tradition
From the roots of two great stories, Mannaceutica was born.
A journey that began in 1828 in Genoa and in 1903 in Palermo, combining tradition and innovation of two entrepreneurial and industrial experiences, today passed down in our brands Mannite Dufour and Iuppa.
From the court of Louis XVI to the lands of Palermo, the story of an entrepreneurial legacy that spans centuries and nations. Dufour of Genoa was founded in 1828. The founder Laurent Dufour, born in Paris in 1763, an official at the court of Louis XVI, came to settle in Turin during the French Revolution as a member of the entourage of the Count of Artois, the future King Charles X. His son Lorenzo, who moved to Genoa, founded the historic Mannite factory in 1828. The Mannite branch of the Dufour Brothers was purchased by the Iuppa family in 1979.
The Mannite and Ash Manna-based products factory of the Iuppa family was founded in Sicily, in 1903, in the city of Palermo. It developed over the course of the last century, and merged with F.lli Dufour Mannite of Genoa in 1979.
Today Luigi Iuppa carries on the tradition of the two historic companies in the innovative project of Mannaceutica that combines past and future, innovation and tradition.
Dufour and Iuppa, two names that whisper family stories, like the wind that caresses the leaves of a centuries-old Ash tree. Between the folds of time, Manna becomes poetry, a precious gift, handed down with love and passion and which today represents innovation, research, unique therapeutic applications and scientific rigor.

Innovation and
research

At the basis of our work today is the awareness that comes from a consolidated historical knowledge, the result of experience, tradition and observation of nature.
Ash Manna, known for centuries for its beneficial properties, represents the central element of our research activities. Through a constant commitment to Research and Development, we deepen this historical knowledge through advanced scientific approaches.
This sense of responsibility led us to create Mannaceutica, which takes on the duty of contributing to overseeing and developing the Science of Manna.
In this way, Mannaceutica integrates tradition and innovation, developing innovative, reliable and sustainable solutions in the field of nutraceuticals, to create exclusive products based on Ash Manna with unique therapeutic indications.
















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