THE FASTEST AND MOST
PHYSIOLOGICAL APPROACH TO CONSTIPATION

It is a dietary supplement that promotes Gastrointestinal Well-being and Transit.

Physiomanna LaxDepur is a
NATURAL and UNIQUE product, made through
a patented manufacturing process, based on
Ash Manna and Mannitol with Osmotic action.
It activates quickly, about 3 hours
after intake.
Mannitol, an important component of
Ash Manna, also present in
all natural plants, is a laxative substance that works by attracting
water into the intestinal lumen, making
the stool softer.

How it works

Ash Manna contains among other components Mannotriose and Mannotetrose,
which contribute to physiologically rebalancing
the microbiome, promoting a targeted prebiotic,
anti-inflammatory and antioxidant action.
Ash Manna is a natural laxative substance free from
contraindications and side effects,
which does not cause dependence and has a strong
detoxifying, choleretic and cholagogue action.
It is therefore also useful for the health
of the liver and bile system.

How to use

Physiomanna LaxDepur is made in soft crystalline blocks that can be dissolved in your favorite drink, giving it a pleasant sweet taste.


It is advisable to take 3 bars dissolved in your favorite drink and then drink a lot of water. It works after a few hours.

OTHER PRODUCTS IN THE PHARMACY

SCIENTIFIC STUDIES

PHENOLIC COMPOSITION OF THE HYDROPHILIC EXTRACT OF MANNA FROM FRAXINUS ANGUSTIFOLIA VAHL SICILIANA AND ITS REDUCING, ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITY IN VITRO

ANTI-PROLIFERATIVE ACTIVITY OF A HYDROPHILIC MANNA EXTRACT FROM FRAXINUS ANGUSTIFOLIA VAHL THROUGH THE MITOCHONDRIAL PATHWAY MEDIATED APOPTOSIS AND CELL CYCLE ARREST IN HUMAN COLON CANCER CELLS

CLINICAL STUDY TAKEN FROM GIGANTE D. – STUDIES AND RESEARCH ON MANNA AND NATURAL MANNITE – STATE POLYGRAPHIC INSTITUTE, 1948.
A PROSPECTIVE, OPEN STUDY ON THE INCREASING DOSE OF A MANNA PREPARATION FOR INTESTINAL CLEANSING IN OUTPATIENT PATIENTS UNDERGOING COLONOSCOPY
MANNITOL FOR BOWEL PREPARATION: PHASE II IDENTIFICATION STUDY DOSE
MANNITOL FOR THE PREPARATION OF THE INTESTINE: RESULTS OF EFFICACY AND SAFETY OF CLINICAL TRIALS RANDOMIZED
FACTORS INFLUENCING THE PRESENCE OF POTENTIALLY EXPLOSIVE GASES DURING COLONOSCOPY: RESULTS OF THE SATISFACTION STUDY
HEALTH POTENTIAL OF POLYOLS AS SUGAR SUBSTITUTES, IN PARTICULAR BEWARE OF LOW PROPERTIES GLYCEMIC CONTENT
WHERE WE ARE

Offices and production plant:

Regione Statione 2A

15010 Alice Bel Colle (AL)

+39 0144 745474

+39 0144 745835

info@mannaceutica.it

© 2026 Mannaceutica Srl
P.IVA IT02758660068

MANNACEUTICA S.R.L. – Company registered in the special section of the Companies Register dedicated to innovative start-ups, pursuant to Article 25, paragraph 8, of Decree-Law No. 179 of 18 October 2012, converted, with amendments, into Law No. 221 of 17 December 2012.

Alessandria-Asti Companies Register – Tax code and registration number 02758660068 – REA AL-314758 – Date of registration in the special section for innovative start-ups: 29 October 2025.

The information required pursuant to Article 25, paragraph 12, of Decree-Law No. 179/2012 is published, pursuant to paragraph 11 of the same Article, in the “Innovative Start-up – Information pursuant to Article 25 of Decree-Law No. 179/2012” section of this website.